Significance of PSA-density : analysis in PSA gray zone cases
We studied the sensitivity and specificity of digital examination and prostate specific antigen (PSA) density to detect prostatic cancer in those patients whose PSA values are in a range of 4 to 10 ng/ml or in a gray zone. Sextant prostate biopsy revealed 14 cases (17.2%) of prostatic cancer out of...
| Publié dans: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 47(2001), 9 vom: 22. Sept., Seite 611-3 |
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| Auteur principal: | |
| Autres auteurs: | , , |
| Format: | Article |
| Langue: | Japanese |
| Publié: |
2001
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| Accès à la collection: | Hinyokika kiyo. Acta urologica Japonica |
| Sujets: | Clinical Trial English Abstract Journal Article Biomarkers, Tumor Prostate-Specific Antigen EC 3.4.21.77 |
| Résumé: | We studied the sensitivity and specificity of digital examination and prostate specific antigen (PSA) density to detect prostatic cancer in those patients whose PSA values are in a range of 4 to 10 ng/ml or in a gray zone. Sextant prostate biopsy revealed 14 cases (17.2%) of prostatic cancer out of 81 PSA gray zone cases. The sensitivity of digital examination was 38.5%, and the specificity was 73.0%. If we use 0.29 as a PSA density cut-off value, the sensitivity was 70.0%, and the specificity was 70.0%. At a PSA density cut off value of 0.22, we could obtain 90% sensitivity, which was considered applicable for detection of cancer in PSA gray zone cases |
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| Description: | Date Completed 14.12.2001 Date Revised 19.11.2015 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |