Automated detection of point mutations by electrophoresis in peptide-nucleic acid-containing gels
Polymerization of electronically, essentially neutral peptide nucleic acids (PNA) into polyacrylamide gels creates a medium in which the salt-independent properties of PNA/DNA interactions are used to achieve hybridization with target DNA during affinity electrophoresis. Such physical entrapment of...
| Publié dans: | BioTechniques. - 1993. - 27(1999), 4 vom: 01. Okt., Seite 798-800, 802, 804 passim |
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| Auteur principal: | |
| Format: | Article |
| Langue: | English |
| Publié: |
1999
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| Accès à la collection: | BioTechniques |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't CFTR protein, human HFE protein, human HLA Antigens Hemochromatosis Protein Histocompatibility Antigens Class I Membrane Proteins Peptide Nucleic Acids Cystic Fibrosis Transmembrane Conductance Regulator plus... |