Oxiconazole in the treatment of vaginal candidiasis : single dose versus 3-day treatment with econazole

Fifty-one women with vaginal candidiasis were included in an open randomized study to compare the efficacy and local tolerance of a single-dose treatment with 600 mg oxiconazole (one vaginal tablet) with that of a 3-day treatment with econazole (one 150 mg ovule daily). Twenty-five patients were tre...

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Veröffentlicht in:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC). - 1995. - 3(1984), 10 vom: 20., Seite 682-5
1. Verfasser: Gouveia, D C (VerfasserIn)
Weitere Verfasser: Jones da Silva, C
Format: Aufsatz
Sprache:English
Veröffentlicht: 1984
Zugriff auf das übergeordnete Werk:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)
Schlagworte:Clinical Trial Comparative Study Journal Article Randomized Controlled Trial Antifungal Agents Imidazoles Econazole 6Z1Y2V4A7M oxiconazole C668Q9I33J
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520 |a Fifty-one women with vaginal candidiasis were included in an open randomized study to compare the efficacy and local tolerance of a single-dose treatment with 600 mg oxiconazole (one vaginal tablet) with that of a 3-day treatment with econazole (one 150 mg ovule daily). Twenty-five patients were treated with oxiconazole and the remaining 26 received econazole. Patients were followed-up 1 week and 4 to 5 weeks after the initial examination and details were recorded of the results of yeast culture, the clinical signs and symptoms present and any signs of intolerance. A cure rate of 92% was achieved in both treatment groups and only 1 patient (econazole group) of the 4 treatment failures (2 in each group) did not respond to a subsequent second course with the same treatment schedule. Vaginal burning was the only reported local side-effect in 5 patients of the oxiconazole group and in 6 of the econazole group 
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