Clinical evaluation of combination therapy with cefoxitin and amikacin in complicated urinary tract infections

The clinical efficacy of combination therapy using Cefoxitin (CFX) and Amikacin (AMK) was studied in 19 patients with complicated urinary tract infections. Patients received 2 g of CFX i.v. and 100 mg of AMK i.m. twice a day. The overall clinical efficacy of treatment was evaluated by the criteria p...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 32(1986), 10 vom: 15. Okt., Seite 1547-50
1. Verfasser: Sakashita, S (VerfasserIn)
Weitere Verfasser: Shinno, Y, Asano, Y, Tubo, S, Imanaka, K, Miyabe, N, Nagamori, S, Takahashi, Y, Koyanagi, T
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1986
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article Cefoxitin 6OEV9DX57Y Amikacin 84319SGC3C
LEADER 01000caa a22002652c 4500
001 NLM035464577
003 DE-627
005 20250126203553.0
007 tu
008 231221s1986 xx ||||| 00| ||jpn c
028 5 2 |a pubmed25n0119.xml 
035 |a (DE-627)NLM035464577 
035 |a (NLM)3565192 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a jpn 
100 1 |a Sakashita, S  |e verfasserin  |4 aut 
245 1 0 |a Clinical evaluation of combination therapy with cefoxitin and amikacin in complicated urinary tract infections 
264 1 |c 1986 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 27.04.1987 
500 |a Date Revised 21.11.2013 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a The clinical efficacy of combination therapy using Cefoxitin (CFX) and Amikacin (AMK) was studied in 19 patients with complicated urinary tract infections. Patients received 2 g of CFX i.v. and 100 mg of AMK i.m. twice a day. The overall clinical efficacy of treatment was evaluated by the criteria proposed by the UTI Committee, Japan, as excellent, moderate or poor. The overall clinical efficacy was excellent in 89%, moderate in 5% and poor in 5% of the patients. Of the 21 strains isolated from the patients, 20 strains (95%) were eradicated. No subjective side effects were observed. Drug-related aggravation in laboratory tests were observed slight elevations of glutomic-oxalacefic transaminase, glutamic-pyruvic transaminase and alkaliphosphatase in 2 cases, but all of them were minimal and reversible. Underlying condition-related aggravation was observed a slight elevation of BUN and creatinine clearance in 1 case. These results suggest that the combination therapy with CFX and AMK might be useful in the treatment of complicated urinary tract infections 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 7 |a Cefoxitin  |2 NLM 
650 7 |a 6OEV9DX57Y  |2 NLM 
650 7 |a Amikacin  |2 NLM 
650 7 |a 84319SGC3C  |2 NLM 
700 1 |a Shinno, Y  |e verfasserin  |4 aut 
700 1 |a Asano, Y  |e verfasserin  |4 aut 
700 1 |a Tubo, S  |e verfasserin  |4 aut 
700 1 |a Imanaka, K  |e verfasserin  |4 aut 
700 1 |a Miyabe, N  |e verfasserin  |4 aut 
700 1 |a Nagamori, S  |e verfasserin  |4 aut 
700 1 |a Takahashi, Y  |e verfasserin  |4 aut 
700 1 |a Koyanagi, T  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Hinyokika kiyo. Acta urologica Japonica  |d 1962  |g 32(1986), 10 vom: 15. Okt., Seite 1547-50  |w (DE-627)NLM012631779  |x 0018-1994  |7 nnas 
773 1 8 |g volume:32  |g year:1986  |g number:10  |g day:15  |g month:10  |g pages:1547-50 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_20 
912 |a GBV_ILN_22 
912 |a GBV_ILN_40 
912 |a GBV_ILN_60 
912 |a GBV_ILN_72 
912 |a GBV_ILN_120 
912 |a GBV_ILN_350 
912 |a GBV_ILN_2001 
912 |a GBV_ILN_2003 
912 |a GBV_ILN_2005 
912 |a GBV_ILN_2006 
912 |a GBV_ILN_2008 
912 |a GBV_ILN_2010 
912 |a GBV_ILN_2012 
912 |a GBV_ILN_2018 
951 |a AR 
952 |d 32  |j 1986  |e 10  |b 15  |c 10  |h 1547-50