Enoxacin concentration in human prostatic tissue

The present study was under taken to evaluate the penetration of enoxacin into prostatic tissue. Ten patients with benign prostatic hypertrophy entered the study. Enoxacin was administered orally at a dose of 200 mg, three times one day before and twice on the day of operation. Blood and urine sampl...

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Détails bibliographiques
Publié dans:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 32(1986), 10 vom: 15. Okt., Seite 1471-3
Auteur principal: Yasumoto, R (Auteur)
Autres auteurs: Kobayakawa, H, Asakawa, M
Format: Article
Langue:Japanese
Publié: 1986
Accès à la collection:Hinyokika kiyo. Acta urologica Japonica
Sujets:English Abstract Journal Article Anti-Infective Agents Naphthyridines Enoxacin 325OGW249P
Description
Résumé:The present study was under taken to evaluate the penetration of enoxacin into prostatic tissue. Ten patients with benign prostatic hypertrophy entered the study. Enoxacin was administered orally at a dose of 200 mg, three times one day before and twice on the day of operation. Blood and urine samples were taken 30 min before operation and prostatic tissue samples were taken during operation. The mean concentration of enoxacin was 4.87 +/- 1.39 micrograms/ml in serum and 5.81 +/- 2.95 micrograms/g in the prostatic tissue. The mean ratio of the prostatic concentration/serum concentration was 1.21 +/- 0.63 (range 0.82-3.00)
Description:Date Completed 27.04.1987
Date Revised 21.11.2013
published: Print
Citation Status MEDLINE
ISSN:0018-1994