High-efficiency cDNA cloning : a comparison of electroporation and in vitro packaging

The production of complete cDNA libraries from minimal amounts of starting material (i.e., mRNA) is a major challenge for cDNA cloning technology. This paper reports the cDNA cloning efficiencies of electroporation and in vitro packaging. These two methods produce a tremendous number of recombinant...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1991. - 12(1992), 6 vom: 08. Juni, Seite 804-6, 808
1. Verfasser: Gruber, C E (VerfasserIn)
Format: Aufsatz
Sprache:English
Veröffentlicht: 1992
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Comparative Study Journal Article
Beschreibung
Zusammenfassung:The production of complete cDNA libraries from minimal amounts of starting material (i.e., mRNA) is a major challenge for cDNA cloning technology. This paper reports the cDNA cloning efficiencies of electroporation and in vitro packaging. These two methods produce a tremendous number of recombinant clones (greater than or equal to 1 x 10(8) clones/micrograms cDNA) although electroporation generates more clones at nearly all cDNA concentrations used in a ligation reaction
Beschreibung:Date Completed 10.09.1992
Date Revised 15.11.2006
published: Print
Citation Status MEDLINE
ISSN:1940-9818