Protein kinase CK2 governs the molecular decision between encephalitogenic TH17 cell and Treg cell development

T helper 17 (TH17) cells represent a discrete TH cell subset instrumental in the immune response to extracellular bacteria and fungi. However, TH17 cells are considered to be detrimentally involved in autoimmune diseases like multiple sclerosis (MS). In contrast to TH17 cells, regulatory T (Treg) ce...

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Veröffentlicht in:Proceedings of the National Academy of Sciences of the United States of America. - National Academy of Sciences. - 113(2016), 36, Seite 10145-10150
1. Verfasser: Ulges, Alexander (VerfasserIn)
Weitere Verfasser: Witsch, Esther J., Pramanik, Gautam, Klein, Matthias, Birkner, Katharina, Bühler, Ulrike, Wasser, Beatrice, Luessi, Felix, Stergiou, Natascha, Dietzen, Sarah, Brühl, Till-Julius, Bohn, Toszka, Bündgen, Georg, Kunz, Horst, Waisman, Ari, Schild, Hansjörg, Schmitt, Edgar, Zipp, Frauke, Bopp, Tobias
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Proceedings of the National Academy of Sciences of the United States of America
Schlagworte:multiple sclerosis TH17 cells regulatory T cells FOXP3 MS therapy