A Chemical Approach to Unraveling the Biological Function of the Glycosylphosphatidylinositol Anchor

The glycosylphosphatidylinositol (GPI) anchor is a C-terminal posttranslational modification found on many eukaryotic proteins that reside in the outer leaflet of the cell membrane. The complex and diverse structures of GPI anchors suggest a rich spectrum of biological functions, but few have been c...

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Détails bibliographiques
Publié dans:Proceedings of the National Academy of Sciences of the United States of America. - National Academy of Sciences. - 104(2007), 51, Seite 20332-20337
Auteur principal: Paulick, Margot G. (Auteur)
Autres auteurs: Forstner, Martin B., Groves, Jay T., Bertozzi, Carolyn R.
Format: Article en ligne
Langue:English
Publié: 2007
Accès à la collection:Proceedings of the National Academy of Sciences of the United States of America
Sujets:Cellular diffusion Glycosylphosphatidylinositol-protein analogs Intracellular trafficking GFP-GPI GPI glycan core Biological sciences Physical sciences