Regulation of Matrix Metalloproteinase-9 and Inhibition of Tumor Invasion by the Membrane-Anchored Glycoprotein RECK

A human fibroblast cDNA expression library was screened for cDNA clones giving rise to flat colonies when transfected into v-Ki-ras-transformed NIH 3T3 cells. One such gene, RECK, encodes a membrane-anchored glycoprotein of about 110 kDa with multiple epidermal growth factor-like repeats and serine-...

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Veröffentlicht in:Proceedings of the National Academy of Sciences of the United States of America. - National Academy of Sciences of the United States of America. - 95(1998), 22, Seite 13221-13226
1. Verfasser: Takahashi, Chiaki (VerfasserIn)
Weitere Verfasser: Sheng, Zeqi, Horan, Thomas P., Kitayama, Hitoshi, Maki, Masatoshi, Hitomi, Kiyotaka, Kitaura, Yasuyuki, Takai, Setsuo, Sasahara, Regina M., Horimoto, Aki, Ikawa, Yoji, Ratzkin, Barry J., Arakawa, Tsutomu, Noda, Makoto
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 1998
Zugriff auf das übergeordnete Werk:Proceedings of the National Academy of Sciences of the United States of America
Schlagworte:Medical Sciences Ras signaling Transformation Metastasis Protease inhibitor Biological sciences Physical sciences Health sciences