Journal Article 82115-62-6 Cell-mediated immunity Influenza Vaccines Interferon-gamma Nicotiana benthamiana Randomized Controlled Trial Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Vaccines, Virus-Like Particle Anti-Retroviral Agents Antibodies, Viral Antigens, Viral Biomarkers Clinical Trial Clinical Trial, Phase I Clinical Trial, Phase II Cross-reactive response HIV Core Protein p24 Influenza Interleukin-2 Long-term memory response Plant-derived quadrivalent influenza vaccine RNA, Viral Safety and immunogenicity Vaccine Virus-like particle Virus-like particles gag Gene Products, Human Immunodeficiency Virus nef Gene Products, Human Immunodeficiency Virus