Journal Article CVID Case Reports Hypogammaglobulinemia Antibodies, Bacterial CRISPR Cas9 CVID-like disorders Cohort studies Common variable immunodeficiency Complement C4 Gene editing Genotoxicity Haemophilus Vaccines Immunoglobulin A Immunoglobulin G Immunoglobulins, Intravenous Pneumococcal Vaccines Research Support, Non-U.S. Gov't Review SCIG/IVIG STAT3 STAT3 Transcription Factor STAT3 protein, human Tetanus Toxoid Vaccine challenge responses Whole exome sequencing