Journal Article Research Support, Non-U.S. Gov't EC 3.1.3.48 Protein Tyrosine Phosphatase, Non-Receptor Type 22 AAb-negative AAb-positive Autoantibodies Autoantibodies (AAb) Autoimmunity Autoreactive cells CXCL13 CXCR5 protein, human Cytotoxic lymphocytes (CTLs); Epitopes, T-Lymphocyte FOXP3 protein, human Follicular Treg cells Forkhead Transcription Factors Genetic predisposition Immune tolerance Isoenzymes Memory CD8(+) T cells; PD-1 PDCD1 protein, human PTPN22 PTPN22 protein, human Programmed Cell Death 1 Receptor Ptpn22 protein, mouse Ptpn22; Receptors, CXCR5 Regulatory T cells (Treg)